In this book, specialists in 11 emerging zoonotic viruses present detailed information on each virus's structure, molecular biology, current geographic distribution, and method of transmission.
Introduction.
Open job opportunities in the humanitarian field. READ ALSO: Lassa Fever Update: NCDC records 472 cases, 70 deaths "The Ministry of Health through Epidemiology, Biosecurity and Global Health Directorate is currently carrying out 'contact .
NIGERIA FIELD EPIDEMIOLOGY AND LABORATORY TRAINING PROGRAMME Prevalence of risk factors for Lassa fever infection in Nasarawa State, Jan 2013 Risk factors Prevalence (95% CI) Presence of rats in the house or immediate surroundings 95.2 (92.5-97.0) Hunting rats 36.7 (32.3-41.6) Consuming rats as protein source 58.1 (53.2-62.9) The book investigates stability theory in terms of two different measure, exhibiting the advantage of employing families of Lyapunov functions and treats the theory of a variety of inequalities, clearly bringing out the underlying theme.
List of alerts, ongoing and past disasters covered by ReliefWeb. Prevalence of symptoms and outcomes among patients with laboratory-confirmed Lassa fever, Nigeria, January 1-May 6, 2018* *aORs and 95% CIs calculated by using a binomial logistic regression model for fatal outcomes adjusted for age and sex.
Oluwatosin Wuraola Akande, Kelly Osezele Elimian, Ehimario Igumbor, Lauryn Dunkwu, Chijioke Kaduru, Olubunmi Omowunmi Olopha, Dabri Olohije Ohanu, Lilian Nwozor, Emmanuel Agogo, Olusola Aruna, Muhammad Shakir Balogun, Olaolu Aderinola, Anthony Ahumibe, Chinedu Arinze, Sikiru Olanrewaju Badaru, William Nwachukwu, Augustine Olajide Dada, Cyril Erameh, Khadeejah Hamza, Tarik Benjamin Mohammed, Nnaemeka Ndodo, Celestina Obiekea, Chinenye Ofoegbunam, Oladipo Ogunbode, Cornelius Ohonsi, Ekaete Alice Tobin, Rimamdeyati Yashe, Afolabi Adekaiyaoja, Michael C. Asuzu, Rosemary Ajuma Audu, Muhammad Bashir Bello, Shaibu Oricha Bello, Yusuf Yahaya Deeni, Yahya Disu, Gbenga Joseph, Chidiebere Ezeokafor, Zaiyad Garba Habib, Christian Ibeh, Ifeanyi Franklin Ike, Emem Iwara, Rejoice Kudirat Luka-Lawal, Geoffrey Namara, Tochi Okwor, Lois Olajide, Oluwafunke Olufemi Ilesanmi, Solomon Omonigho, Ferdinand Oyiri, Koubagnine Takpa, Nkem Usha Ugbogulu, Priscilla Ibekwe, John Oladejo, Elsie Ilori, Chinwe Lucia Ochu, Chikwe Ihekweazu.
Nigeria | EIDB The confirmed and suspected cases of Lassa fever virus has spiraled over the last 3 years. However, young age and pregnancy are associated with . PDF Molecular Epidemiology of Lassa Fever in Edo State, Nigeria A number of epidemiological studies reported on the Lassa fever outbreak in Nigeria in 2018.
During the second wave, confirmed COVID-19 cases increased among females and people 30 years old or younger and decreased among urban residents and individuals with travel history within 14 days of sample collection (p value <0.001).
Viral hemorrhagic fevers have captured the imagination of the public and made their way into popular books and movies by virtue of their extreme virulence and mysterious origins.
Increasing international travel and the possibility of use of the Lassa virus as a biological weapon escalate the potential for harm beyond the local level. Current Molecular Epidemiology of Lassa Virus in Nigeria䌤§ Deborah U. Ehichioya,1,2,3 Meike Hass,2 Beate Becker-Ziaja,2 Jacqueline Ehimuan,4 Danny A. Asogun,4 Elisabeth Fichet-Calvet,2 Katja Kleinsteuber,2 Michaela Lelke,2 Jan ter Meulen,5† George O. Akpede,4 Sunday A. Omilabu,1 Stephan Gu ¨nther,2* and Stephan O ¨ lschla¨ger2 . Lassa fever (LF), caused by Lassa virus (LASV), is increasingly recognised as an important rodent-borne viral haemorrhagic fever presenting a severe public health threat to some of the communities in sub-Saharan West Africa [1]. Lassa fever is a high consequence infectious disease (HCID). The Lassa fever is a member of are naviridiae virus family like Ebola; clinical cases of the disease had been known for longer than three decades but had .
Canada Medical Careers: Recruiting GP’s for GREAT positions across Canada! Epidemiology of Lassa Fever •Incubation period: 6-21 days •Period of communicability : Person to person spread occur during the acute febrile phase when virus is present in the throat •Virus may be excreted in urine of patients for 3-9 weeks from
Large-scale Lassa fever outbreaks in Nigeria: quantifying ...
This successful book, now in its third edition, continues to provide a comprehensive introduction to the role of epidemiology in veterinary medicine. Lassa fever (LF) is an acute febrile disease caused by the Lassa virus, a member of the family Arenaviridae, whose natural hosts are rodents of the genus Mastomys.,, The disease is estimated to affect 2 million people and cause an estimated 5000-10,000 deaths annually with outbreaks reported from Sierra Leone, Guinea, Liberia, and Nigeria.,,,, Humans become infected through direct contact with .
Is an acute and often fatal viral disease, with fever, occurring mainly in West Africa. CFR decreased during the second wave (0.7%) compared with the first wave (1.8%).
Find help on how to use the site, read terms and conditions, view the FAQs and API documentation. 8, no. In this article, we report an analysis of the epidemiologic and clinical aspects of the LF outbreak that occurred in Nigeria during January 1-May 6, 2018.
2 . NCDC Lassa fever Situation Report Epi Week 45: 8-14 November 2021 Format Situation Report Source. Curated pages dedicated to humanitarian themes and specific humanitarian crises. The Nigeria Centre for Disease Control (NCDC) was established in the year 2011 in response to the challenges of public health emergencies and to enhance Nigeria’s preparedness and response to epidemics through prevention, detection and control of communicable diseases. This book covers topics such as AeroSpace Systems, Intelligent Systems, Machine Learning and Analytics, Internet of Things, Applied Media Informatics and Technology, Adaptive Control Systems, Software Engineering and Cyber-Physical Systems. Published. クライアント企業のスポット的ニーズにお応えします。, 採用支援だけでなく、業務プロセスの再構築や組織設計といった企業経営を Descriptive statistical measures including frequencies and percentages, test positivity rate (TPR), cumulative incidence (CI) and case fatality rates (CFRs) were compared. From 1 January to 28 April 2019, 554 laboratory-confirmed cases including 124 deaths were reported in 21 states in Nigeria.
Lassa fever is a zoonotic disease spread by infected rodents known as multimammate rats. We analyzed LF surveillance data from January 2014 to December 2019 to describe the epidemiological pattern of the outbreak. The Lassa Ward is more than just an adventure story about the making of a physician; it is a portrait of the Sierra Leone people and the human struggle of those risking their daily comforts and lives to aid them. Lassa fever is a hemorrhagic . In this article, we report an analysis of the epidemiologic and clinical aspects of the LF outbreak that occurred in Nigeria during January 1-May 6, 2018. Of the cases reported so far in the Nigerian outbreak, the mortality rate is 43.2%5 although the typical mortality rate is thought to be closer to 1-15%6. This work is a critical reflection on the state of health promotion effectiveness in practice around the world. 5 The prevalence of antibodies to the virus in the population is 8-52% in Sierra Leone, 6 4-55% in Guinea, 7 and 21% in Nigeria.
This volume offers an overview of the processes of zoonotic viral emergence, the intricacies of host/virus interactions, and the role of biological transitions and modifying factors. We aimed to compare the epidemiological features of the first and second waves of COVID-19 in Nigeria. p values calculated by using a binomial logistic regression model and adjusted by the Bonferroni . Continued implementation of public health and social measures is needed to mitigate the resurgence of another wave. Introduction. Having attained a high level of international recognition, is an emerging fast-spreading disease with the possibilities of causing epidemics. In most endemic regions of Africa, it is recorded year-round, with a slight increase in incidence in January-February (the period of migration of rodents to human habitation).
Lassa fever, also known as Lassa hemorrhagic fever (LHF), is a type of viral hemorrhagic fever caused by the Lassa virus.
Euro Surveillance.
New treatments are needed to decrease mortality, but pretrial reference data on the disease characteristics are scarce.
The Psychosocial Aspects of a Deadly Epidemic: What Ebola ...
We investigated the outbreak to determine factors associated with being a confirmed Lassa fever case and the health seeking .
It has been known since the 1950s, but the virus was not identified until 1969, when two missionary nurses died from it in the town of Lassa in Nigeria. ii molecular epidemiology of lassa fever in edo state, nigeria by ehichioya, deborah uwa. Name of the Student: Course and Title: Instructors Affiliation: Professors Name: Due Date . A review of Lassa fever outbreaks in Nigeria From 1969 to 2017: Epidemiologic profile, determinants and public health response. Endemic hotspots within these countries have had recurrent exposure to Lassa virus (LASV) via continual spillover from the host reservoir Mastomys natalensis.
2001;1:269-82.
Access this article for 1 day for:£30 / $37 / €33 (excludes VAT). The study was an observational study of laboratory- confirmed patients during the 2016 outbreak. 2018;27: 219-233-233. Ilori et al. Lassa Fever.
Kofman A, Choi MJ, Rollin PE.
Endemic hotspots within these countries have had recurrent exposure to Lassa virus (LASV) via continual spillover from the host reservoir Mastomys natalensis. Discovered in 1969 [2], LF is endemic to much of rural Nigeria and regions in the Mano River Union [3].
It is endemic in the West African countries of Sierra Leone, Guinea, Liberia, and Nigeria ([2,3] and references therein). Less commonly there may be bleeding from the mouth or gastrointestinal tract. In this volume, a distinguished international group of contributors present the latest molecular, organismal, and epidemiological research on arenaviruses. PDF Lassa fever: History, causes, effects, and reduction ... doi: 10.12691/ajphr-8-4-3. Please note: your email address is provided to the journal, which may use this information for marketing purposes.
Annually, about 300,000-500,000 people are being infected, with about 5000 deaths.
This volume examines the most important socio-cultural, political, economic, and policy issues related to emerging infectious diseases in Africa.
Latest humanitarian reports, maps and infographics and full document archive. The illness was discovered in 1969 when two missionary nurses died in Nigeria. The sources of information were a literature review using Ovid and PubMed (search term “Lassa fever”), case analysis and surveys undertaken in the field, and relevant websites (such as those of the World Health Organization, Centers for Disease Control and Prevention).
A national upsurge in Lassa fever cases and death occurred in January 2019, with Eguare community in Esan West Local Government Area, Edo State having an unusual increase in number of reported cases.
The seroprevalence of Lassa fever in Nigeria is 21% (7). The perspective represented by this book, that of medical virology as an infectious disease science, is meant to provide a starting point, an anchor, for those who must relate the subject to clinical practice, public health practice, ... Map Nigeria showing distribution of confirmed Lassa fever cases in Nigeria, 2019. Lassa fever (LF) is predominant in West Africa including Sierra Leone, Liberia and Nigeria . CI during the first and second waves were 30.3/100 000 and 42.0/100 000 respectively. The viruses are now known to contain a single positive strand of RNA. About 50% of corona virus infections result in clinical illness. About 5% of common colds are caused by strain DC 43 in winter. A public health emergency was declared on 22 January by the Nigeria Centre for Disease Control.
A national upsurge in Lassa fever cases and death occurred in January 2019, with Eguare community in Esan West Local Government Area, Edo State having an unusual increase in number of reported cases.
In Nigeria, between August 2015 and 17 May 2016 there have been 273 cases of Lassa fever, including 149 Deaths in 23 states. A national upsurge in Lassa fever cases and death occurred in January 2019, with Eguare community in Esan West Local Government Area, Edo State having an unusual increase in number of reported cases. Lassa and Lujo fevers: Global Status is one in a series of GIDEON ebooks which explore all individual infectious diseases, drugs, vaccines, outbreaks, surveys and pathogens in every country of the world. Lassa fever 1. Introduction.
To have a deeper understanding of Lassa fever epidemiology in Nigeria, we present a deterministic dynamical model to study its dynamical transmission behavior in the population. Introduction. However, only 11 (32%) LASV infections were confirmed by RT-PCR. It is usually acquired from infected rats. Abstract. It is commonly found in the West African countries, including Nigeria, Ghana, and Liberia, among other countries. This acute viral hemorrhagic fever brought about by the Lassa infection which was first described in 1969 and named after the town of Lassa (Yedseram River valley), in Borno State, Nigeria. 3. The Lassa fever is a member of are naviridiae virus family like Ebola; clinical cases of the disease had been known for longer than three decades but had . From January to September 2021, there were in Nigeria 369 confirmed cases of Lassa fever and over three thousand suspected cases. Learn more about ReliefWeb, leading online source for reliable and timely humanitarian information on global crises and disasters since 1996. Neighboring countries are also at risk, as the animal vector for Lassa virus, the "multimammate rat" (Mastomys natalensis) can be found in the other countries in the region.
Lassa fever in Guinea, West Africa. Epidemiology. View Article Google Scholar 13. The history of recognized human arenavirus infection in Africa began in 1969 with the mysterious death of two medical missionaries and the near-fatal illness of a third (Frame et al. Vector Borne and Zoonotic Diseases. Lassa fever (LF), one of the severe viral hemorrhagic fevers (VHF), was first reported from Nigeria in 1969 ().Since then, there have been repeated outbreaks in Nigeria and other West African countries (3, 4), particularly Sierra Leone and Liberia but also Togo (), and the Republic of Benin ().In addition, LF is the most exported VHF, particularly to Europe (4, 7, 8) and America . Lassa fever (LF) is endemic to Nigeria, where the disease causes substantial rates of illness and death. 1. This volume covers major aspects of Crimean-Congo hemorrhagic fever (CCHF) and the virus which causes it. Lassa fever cases have increased in Nigeria since 2016 with the highest number, 633 cases, reported in 2018. Crowcroft N. Management of Lassa Fever in European countries. Cases imported to Europe indicate that Lassa fever also occurs in Coˆte d'Ivoire and Mali [4,5]. Lassa fever (LF) outbreaks in Nigeria mostly occur in rural areas and during the dry season, peaking between December through February.
1970). Most confirmed cases were asymptomatic at diagnosis during both waves: 74.9% in the first wave; 79.7% in the second wave.
From 1 January through 10 February 2019, 327 cases of Lassa fever (324 confirmed cases and three probable cases) with 72 deaths (case fatality ratio = 22%) have been reported across 20 states and the Federal Capital Territory, with the majority of cases being reported from Edo (108) and Ondo (103) States. Contributed articles. This volume, representing a compilation of authoritative reviews on a multitude of uses of statistics in epidemiology and medical statistics written by internationally renowned experts, is addressed to statisticians working in biomedical ... This is as the Nigeria Centre for Disease . When symptoms occur they typically include fever, weakness, headaches, vomiting, and muscle pains. This book fills this gap by offering a much needed political economy analysis of zoonosis research and policy. Through ethnographic, qualitative and quantitative data, the book draws together a diverse number of case studies. It is generally . fever that is caused by the Lassa virus, which is an enveloped RNA virus from the Arenavirus family of viruses [1,2].
1970). Frequency (Epidemiology): Lassa fever frequently infects people in West Africa with about 80% being asymptomatic, studies show up to 300, 000 - 500, 000 cases annually and causes about 5,000 deaths. This manual provides concise and up-to-date knowledge on 15 infectious diseases that have the potential to become international threats and tips on how to respond to each of them. The 21st century has already been marked by major epidemics. With reports of surges in COVID-19 case numbers across over 50 countries, country-level epidemiological analysis is required to inform context-appropriate response strategies for containment and mitigation of the outbreak. University Hospitals Sussex NHS Foundation Trust: Consultant in Complex Spinal Surgery Orthopaedic or Neurosurgical, University Hospitals Sussex NHS Foundation Trust: Consultant Medical Microbiologist and Infectious Diseases, NHS Tayside: Consultant in Breast Medical Oncology, Women’s, children’s & adolescents’ health.
Found predominantly in west Africa,1 it has the potential to cause tens of thousands of deaths. The epidemiology of Lassa Fever is gradually changing towards assuming an endemic dimension despite several evidence-based efforts taken by stakeholders towards disease control.
The Infectious Disease Vulnerability Index is intended to inform actions for preparedness and response to infectious disease outbreaks and foster greater resiliency of national health systems worldwide. Lassa fever, Nigeria, 2003 and .
Access your account or create a new one for additional features or to post job or training opportunities. The IOM's Forum on Microbial Threats hosted the workshop "Globalization, Movement of Pathogens (and Their Hosts) and the Revised International Health Regulations" December 16-17, 2008 in order to explore issues related to infectious disease ... An award-winning genetic researcher and a tenacious journalist examine each phase of the Ebola epidemic in West Africa, the largest and deadliest of its kind. Fever is a cardinal presenting feature among the myriad manifestations of LF. technical support for your product directly (links go to external sites): Thank you for your interest in spreading the word about The BMJ.
Omilabu SA, Badaru SO, Okokhere P, Asogun D, Drosten C, Emmerich P, et al. LASSA FEVER What is Lassa fever?
It affects 100,000 to 300,000 people every year in this region [ 3 ]. The history of recognized human arenavirus infection in Africa began in 1969 with the mysterious death of two medical missionaries and the near-fatal illness of a third (Frame et al. We describe the various outbreak responses that have been . There was a 21.3% increase in the number of tests conducted in the second wave with TPR increasing by 14.3%.
Crimean-Congo Hemorrhagic Fever: A Global Perspective
Finally, all these characteristics make this book an excellent update on many subjects of world public health.
The One Health approach to incident management of the 2019 ...
Students of tertiary institutions are also exposed to risk factors.
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Copyright © 2021 BMJ Publishing Group Ltd 京ICP备15042040号-3, Lassa fever: epidemiology, clinical features, and social consequences, https://doi.org/10.1136/bmj.327.7426.1271, Taurus Healthcare: Flexible opportunities for GPs.
Introduction: Lassa fever disease is endemic in Edo State, Nigeria. The Nigeria Field Epidemiology and Laboratory Training Program, a public health workforce development strategy, is also an important intervention aimed at promoting the One Health approach which continuously builds the capacity of medical doctors, veterinarians, laboratory scientists and environmental Symptoms of LF include high grade fever, headache, malaise, abdominal pain, vomiting, diarrhea, or sore throat. Date.
8 Seropositivity has also been . This book aims to bring the focus back to these marginal populations to reveal the often unintended consequences of current policy responses to epidemics. Akhuemokhan et al (8) studied prevalence of Lassa fever disease (LFD) in febrile children aged one month and above to 15 years of age in Irrua specialist hospital and reported a total prevalence rate of 5.7%.Webb et al (9) carried out a similar study among children and reported a . Of these, 66 121 (18.2%) and 91 644 (20.8%) tested positive in the first and second waves, respectively.
29 October 2021.
Increasing evidence of emerging and re-emerging zoonotic diseases including recent Lassa fever outbreaks in almost 20 states in Nigeria led to 101 deaths and 175 suspected and confirmed .
An update of Lassa fever outbreak in Nigeria for Week 44.
We do not capture any email address. The information presented comes from a strategic document produced in 2002 for Merlin Background: Lassa fever disease is endemic in Edo State, Nigeria. Epidemiology Lassa fever is endemic in parts of West Africa, particularly Guinea, Liberia, Nigeria and Sierra Leone, where the animal . Edited by a clinical psychologist who has been on the ground helping to develop psychosocial support for Ebola survivors in one of the hardest-hit regions of West Africa, this book explains the devastating emotional aspects of the epidemic ... The virus is transmitted to humans
There were 802 143 tests recorded during the study period (362 550 and 439 593 in the first and second waves, respectively). 2002;7(3):50-2. Epidemiologic and Clinical Features of Lassa Fever ... Previously, Outbreak Thursday has covered a handful of Lassa fever outbreaks in West Africa, namely ongoing outbreaks in Lassa fever-endemic Nigeria.Although the West African region has experienced fluctuating transmission and periods of low incidence, the ability to quickly diagnose Lassa fever cases has been hindered by nonspecific clinical presentation and inadequate data on virus infection . Lassa fever was first recognized in Lassa, Nigeria, in 1969 and is endemic to West Africa; there are approximately 300,000 cases and 5000 deaths annually [ 4-12 ]. PDF Molecular Diagnostics for Lassa Fever at Irrua Specialist ... Open training opportunities in the humanitarian field.
Introduction . Nigeria experienced a larger but less severe second wave of COVID-19.
Lassa fever, like many infectious diseases, has both epidemiological and Ehichioya DU, Hass M, Becker-Ziaja B, Ehimuan J, Asogun DA, Fichet-Calvet E, et al. We aimed to document baseline characteristics and outcomes for patients hospitalised with Lassa fever in Nigeria. Lassa fever is a disease with an average level of contagiousness, but a high mortality rate (from 18 to 60%). Words: Lassa fever, Outbreak Response, Incident Management System, Nigeria Lassa fever (LF) is a severe acute viral hemorrhagic illness caused by a virus belonging to the family Arenaviridae.
Tropical Infectious Diseases: Principles, Pathogens & Practice It is commonly found in the West African countries, including Nigeria, Ghana, and Liberia, among other countries.
Find latest updates on global humanitarian responses, Nigeria Food Security Outlook, October 2021 to May 2022, The United States and Nigeria: Strategic Partners, IOM Nigeria: COVID-19 Situation Analysis 5: North Central and North West Zones (November 2021), NCDC Lassa fever Situation Report Epi Week 45: 8-14 November 2021.
The . Lassa Fever in Travelers from West Africa, 1969-2016.
4 (2020): 118, vol-121. ReliefWeb Labs projects explore new and emerging opportunities to improve information delivery to humanitarians.
I.
Lassa fever (LF) is an acute, viral hemorrhagic illness which is common in West Africa.
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